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Osteosarcoma is the most common bone tumor of dogs and cats. It most commonly affects large or giant breed dogs. The most common sign that a pet with osteosarcoma may display is a persistent lameness that does not respond to symptomatic therapy such as exercise restriction or aspirin-like pain medication. It can usually be diagnosed with a combination of X-rays of the affected limb and evaluation of a sample of tissue from the affected area of bone by means of a biopsy.
Treatment of canine osteosarcoma consists of limb amputation to remove the diseased bone, followed by chemotherapy to delay or prevent the appearance of metastasis (spread). In cases where amputation is not possible or is declined, improvement in symptoms can be achieved through the use of radiotherapy. [link to radiation therapy info]
Previous clinical trials for canine osteosarcoma performed at the UW have included evaluations of novel immunotherapy compounds, and new chemotherapy agents.
back to the Oncology Service
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